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We interviewed parents of vaccine-eligible girls attending medical appointments in an urban academic medical center and an affiliated community health center.

We used qualitative methods to explore parents' opinions about mandating routine childhood vaccines and HPV vaccine, as well as their feelings about vaccinating their own daughters against HPV.19 Caucasian, 18 African-American, 12 Afro-Caribbean, 3 African, and 21 Latino parents participated.

Responses to qualitative questions were audiotaped and transcribed.

Spanish responses were transcribed in Spanish, translated to English by one bilingual investigator, and then reviewed by a second bilingual investigator to ensure the adequacy of translation.

Intention to vaccinate was assessed by asking parents to rate their likelihood of accepting vaccination for their daughters on a 4-point scale.

Qualitative questions were developed on the basis of research by Mays and colleagues (2004) and tailored for cultural relevance to our sample of parents.

led most states to abandon efforts to mandate vaccination. Prior experience with varicella and Hepatitis B vaccination indicates that requiring vaccination for school entry leads to greater public uptake of vaccine recommendations (Davis and Gaglia 2005; Morita, Ramirez et al. Mandating vaccinations has also been shown to reduce racial disparities in both vaccination rates (Morita, Ramirez et al.

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Over 11,000 women in the United States develop cervical cancer each year, and an additional 330,000 women annually undergo surgical procedures to remove precancerous lesions of the cervix (American Cancer Society 2008; Schiffman and Solomon 2003).

Interviews were conducted in both English and Spanish by native speakers.

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