More sedating

02-Jul-2016 06:50

The ideal sedative would exhibit all of the above qualities; most do not.

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Stimulation of this receptor potentiates the inhibitory effects of gamma-aminobutyric acid (GABA) on GABA-A receptors.

This results in chloride influx, hyperpolarization, and decreased ability of the neuron to reach an action potential, producing sedation and anxiolysis.

In addition, this class of drugs produces amnesia and has anticonvulsant actions. Their most significant adverse effect is respiratory depression and subsequent hypoxemia.

This determines the equipment that one should have readily available prior to starting the procedure.

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Individual patient response to medications can vary; therefore, the clinician can potentially overshoot the desired level of anesthesia.Has a currently accepted medical use in treatment in the United States.